By Terry F. Davies
In A Case-Based Guide to Clinical Endocrinology, Second variation, a well known team of unusual clinicians once back offers stimulating instruction and insights into a large choice of endocrine topics, teaching readers modern administration of the stipulations defined and offering certain access into the literature. Importantly, a few of the vital components within the present curriculum for medical endocrine education as prompt via the organization of application administrators in medical Endocrinology, Diabetes and Metabolism are coated during this textual content. completely up-to-date, this re-creation not just covers new therapy ways but in addition emphasizes the newest investigative advances in either imaging and molecular diagnostics. to enhance studying and retention of information, a question-based method is utilized in a number of the case experiences. scholars, citizens, fellows, and practitioners will locate this connection with be a good method to assessment their understanding and raise their skills and abilities in sufferer research and administration. a useful contribution to the sphere, A Case-Based Guide to Clinical Endocrinology, Second Edition, deals an identical comprehensive volume of thought-provoking case-studies that made the 1st version of vital significance to all clinicians who deal with sufferers with endocrine disorders.
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Extra info for A Case-Based Guide to Clinical Endocrinology
2012;26:447–60. 4. Fleseriu M. Medical management of persistent and recurrent cushing disease. Neurosurg Clin N Am. 2012;23:653–68. 5. Fleseriu M. The role of combination medical therapy in acromegaly: hope for the nonresponsive patient. Curr Opin Endocrinol Diabetes Obes. 2013;20:321–9. 6. Fleseriu M, Biller BM, Findling JW, Molitch ME, Schteingart DE, Gross C. Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing’s syndrome. J Clin Endocrinol Metab.
Several investigators have recommended serial measurement of serum cortisol in the days after pituitary surgery to identify patients with persistent CD. All therapeutic options were discussed with this patient’s case: medication, bilateral adrenalectomy (BLA), or repeat transsphenoidal surgery (TSS). Transsphenoidal surgery in the hands of an experienced surgeon has demonstrated remission rates of between 65 and 93 % when used as first-line therapy. However, even with immediate re-exploration, after nonremission, rates drop to about 50 %.
If a diagnosis had been made earlier, this patient would most likely have avoided the development of vision loss and joint damage and he may have avoided several cosmetic procedures. Additionally, early alterations from excess GH causes joint thickness, which can be reversed with treatment, whereas later boney complications are irreversible even with disease control and in the case of this patient may translate to permanent skeletal disabilities. How Was the Diagnosis of GH Excess (Acromegaly) Made?
A Case-Based Guide to Clinical Endocrinology by Terry F. Davies