By Y. Nakamura, H. Miyashita, O. Iimura, K. Ueda, T. Sugimoto, Y. Toyama (auth.), Prof.Dr. David T. Kelly (eds.)

ISBN-10: 3540513884

ISBN-13: 9783540513889

ISBN-10: 3642749119

ISBN-13: 9783642749117

These are the complaints of the 3rd Asian Pacific Adalat Symposium. the 1st was once held in Tokyo in 1982 and the second one in Sydney in 1985. We have been honoured that the overdue Dr. Sukaman and his colleagues have been in a position to host this 3rd symposium in Jakarta. This assembly used to be designed to give a contribution to and to advertise overseas collaboration in cardiovascular learn, and to assist advertise additional wisdom and knowing concerning the therapy of vascular illness within the Asian Pacific region. Nifedipine used to be initially investigated within the mid-1960s by means of Prof. Fleckenstein. His first effects confirmed this drug was once a robust calcium antagonist which altered excitation contraction. at the present, there has been a quick improvement of information in regards to the pathophysiology of ischaemic middle sickness, and therefore the $64000 pharmacological paintings on calcium antagonists reminiscent of nifedipine paralleled and complimented the more recent realizing of coronary body structure in guy. very quickly so much remedy used to be designed to minimize myocardial oxygen intake and demand.

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Additional info for Adalat® in the Asian Pacific Region

Sample text

Of Medicine, Toyama Medical and Pharmaceutical University, Faculty of Medicine, Toyama, Japan Effect of Nifedipine on Relaxation 35 technique. A pacing catheter was then positioned in the right atrium and a high fidelity micromanometer-tipped angiocatheter (Milcro-tip, model PC481, Millar Instruments) was introduced into the left ventricle. Baseline drift was checked by comparison with a Statham P23Db transducer connected to the catheter's fluid-filled lumen for angiography. The zero level of the fluid system was set at the midchest position.

Am J Cardiol 41 :631 36. Epstein SF, Palmeri ST, Patterson RE (1982) Evaluation of patients after acute myocardial infarction. Indications for cardiac catheterization and surgical intervention. N Engl J Med 307: 1487 37. Frazier J, Cooper N, Buckberg G (1974) The adequacy of subendocardial oxygen delivery; the interaction of determinants of low arterial oxygen content and myocardial oxygen need. Circulation 49:968 38. Mair TW (1972) Subendocardial distribution of coronary blood flow and the effect of antianginal drugs.

1985) Improved survival after early thrombolysis in acute myocardial infarction. A randomized trial conducted by the Interuniversity Cardiology Institute in the Netherlands. Lancet ii 578-582 19. Hugenholtz PG, Serruys PW, Fleckenstein A et al. (1986) Why Ca2+ antagonists will be most useful before or during early myocardial ischemia and not after infarction has been established. Eur Heart J 7:270-278 20. Simes PA, Overskeid K, Pedersen TR, Bathen J, Drivenes A, Froland Gs, Kjekshus JK, Landmark K, Rokseth R, Simes KE, Sund0Y A, Torjussen BR, Westlund KM, Wik BA (1984) The Norwegian Nifedipine Multicenter Trial.

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Adalat® in the Asian Pacific Region by Y. Nakamura, H. Miyashita, O. Iimura, K. Ueda, T. Sugimoto, Y. Toyama (auth.), Prof.Dr. David T. Kelly (eds.)

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